Fisics-Incor Bovine Pericardial Bioprostheses: 15 Year Results

(#1997-RB154)

Pablo M. A. Pomerantzeff, Carlos M. A. Brandao, Paulo Cauduro, Luiz Boro Puig, Max Grinberg, Flavio Tarasoutchi, Luis F. Cardoso, Adolfo Lerner, Noedir A. G. Stolf, Geraldo Verginelli, Adib D. Jatene

Heart Institute, Hospital das Clínicas, Medical School, University of São Paulo, São Paulo, Brazil.

ABSTRACT

Background: From March 1982 to December 1995, 2,607 Fisics-Incor bovine pericardial bioprostheses were implanted in 2,259 patients. Mean age was 47.2 ± 17.5 years, and 55% were male. Rheumatic fever was present in 1,301 (45.7%) patients.

Methods: One thousand and seventy-three aortic valve replacements, 1,085 mitral replacements, 27 tricuspid replacements, 195 mitral-aortic replacements, and 16 other combined valve replacements were carried out. Combined procedures were performed in 788 (32.9%) patients, the most frequent being tricuspid valve repair (9.2%) and coronary artery bypass grafting (7.7%).

Results: Hospital mortality was 8.6% (194 patients), 8.6% for the mitral group, 4.7% for the aortic group, and 12.8% for double-valve replacements. The linear rates for calcification, thromboembolism, rupture, leak and endocarditis were, respectively, 1.1%, 0.2%, 0.9%, 0.1% and 0.5% patient-year. The actuarial survival curve was 56.7 ± 5.4% in 15 years. Survival free from endocarditis was 91.92%, survival free from thromboembolism was 95 ± 1.7%, survival free from rupture was 43.7 ± 9.8%, survival free from leak was 98.9 ± 4.5%, and survival free from calcification was 48.8 ± 7.9% in 15 years. In the late postoperative period, 1,614 (80.6%) patients were in New York Heart Association functional Class I.

Conclusions: We conclude that the results with the Fisics-Incor bovine pericardial prostheses were satisfactory in our group of patients.

AUTHOR/ARTICLE INFORMATION

Translated and reproduced with permission from Revista Brasileira De Cirurgia Cardiovascular; 12(4): 359-66. Copyright 1997 Pablo M. A. Pomerantzeff, et al.

Address correspondence and reprint requests to: Pablo M. A. Pomerantzeff, Av. Dr. Enéas de Carvalho, Aguiar, 44 - Divisão Cirúrgica, São Paulo - SP, Brazil, CEP: 05403-900